Marmara Pharmaceutical Journal 2017 , Vol 21 , Issue 4
Preparation and characterization of herbal emulsion formulations
1Ege University, Faculty of Pharmacy, Department of Pharmaceutical Technology, PK 35100, Bornova/İzmir, Türkiye
2Republic of Turkey Ministry of Health, Turkish Medicines and Medical Devices Agency, Söğütözü Mahallesi 2176.Sokak No:5 PK 06520 Çankaya/Ankara, Türkiye
DOI : 10.12991/mpj.2017.2 St John"s wort extract (Hypericum perforatum L. aerial part extract), marigold extract (Calendula officinalis L. flower extract), wheat germ oil (Triticum vulgare Vill. germ oil) and rose oil (Rosa damascena Mill. volatile oil) have antiinflammatory, antimicrobial and wound healing properties. In this study, it is aimed to prepare and characterize herbal topical emulsion formulations for skin disorders with these herbal extracts and oils. Initially the compatibility of herbal ingredients was evaluated and the design of formulation as an emulsion was studied. Then decided cream formulations were prepared as o/w type emulsions. The formulations characterized via several parameters such as; macroscopic and microscopic observations, pH, electrical conductivity and rheological measurements. The characterization of prepared three formulations revealed acceptable properties while one of them had better applicability, maintained its macroscopic stability in room conditions for 6 months, had appropriate pH and electrical conductivity values and had pseudoplastic flow properties. As conclusion, a topical emulsion formulation was prepared with appropriate properties. Keywords : Topical delivery; herbal formulations; emulsion; St John